LIM Domain Kinase 1/2 (LIMK1/2) (pThr505) anticorps (Biotin)

N° du produit ABIN2177318

L’anticorps Lapin Polyclonal anti- a été validé pour WB, ELISA, IHC (p) et IHC (fro). Il convient pour détecter dans des échantillons de Rat.

Aperçu rapide pour LIM Domain Kinase 1/2 (LIMK1/2) (pThr505) anticorps (Biotin) (ABIN2177318)

Antigène: LIM Domain Kinase 1/2 (LIMK1/2)

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit

Épitope: pThr505

Réactivité croisée: Rat

Homologie: Human,Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human LIMK1 and LIMK2 around the phosphorylation site of Thr508 and Thr505

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détail du antigène

Antigène: LIM Domain Kinase 1/2 (LIMK1/2)

Autre désignation: LIMK1LIMK2

Sujet:

Synonyms: LIMK1Thr508, EC 2.7.11.1, LIM domain kinase 1, LIM mot-containing protein kinase, LIMK, LIMK-1, LIMK2, LIMK-2, LIM domain kinase 2, LIMK1_HUMAN.

Background: LIMK1 is a protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. LIMK1 may be involved in brain development, it is highly expressed in both adult and fetal nervous system. Detected ubiquitously throughout the different regions of adult brain, with highest levels in the cerebral cortex. Expressed to a lesser extent in heart and skeletal muscle.

ID gène: 3984