MAP4K4 anticorps (pSer629) (PE)

N° du produit ABIN2177518

Cet anticorps Lapin Polyclonal détecte spécifiquement MAP4K4 dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MAP4K4 anticorps (pSer629) (PE) (ABIN2177518)

Antigène: MAP4K4 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MAP4K4 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-MAP4K4 anticorps (PE)

Épitope: pSer629

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human MAP4K4 around the phosphorylation site of Ser629

Isotype: IgG

Information d'application

Indications d'application: FCM: (1:20-100)
Optimal working dilution should be determined by the investigator.

Commentaires:

Exitation/Emission: 480,565nm/578nm

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at 4 °C for 12 months.

Détails sur MAP4K4

Antigène: MAP4K4 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4 (MAP4K4))

Autre désignation: Map4k4

Sujet: MAP4K4 (Mitogen-activated protein kinase kinase kinase kinase 4) belongs to the serine/threonine protein kinase family and specifically activates MAPK8/JNK. It may play a role in the response to environmental stress and is thought to function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF alpha signaling pathway. It interacts with the SH3 domain of the adapter protein Nck. MAP4K4-dependent signaling inhibits PPARG responsive gene expression, adipogenesis, and insulin stimulated glucose transport.
Synonyms: MAP4K4phospho S629, Hepatocyte progenitor kinase like/germinal center kinase like kinase, HGK, HPK/GCK like kinase, HPK/GCK like kinase HGK, KIAA0687, MAPK/ERK kinase kinase kinase 4, MEK kinase kinase 4, MEKKK 4, MEKKK4, Mitogen activated protein kinase kinase kinase kinase 4, Nck interacting kinase, NIK.

ID gène: 9448