INTU anticorps (AA 320-350)
Aperçu rapide pour INTU anticorps (AA 320-350) (ABIN2178384)
Antigène
Voir toutes INTU AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 320-350
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Réactivité croisée
- Humain, Souris, Rat
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human PDZD6
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Isotype
- IgG
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Indications d'application
- WB 1:300-5000
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- INTU (Inturned Planar Cell Polarity Effector Homolog (INTU))
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Autre désignation
- PDZD6
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Sujet
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Synonyms: Protein inturned, Inturned planar cell polarity effector homolog, PDZ domain-containing protein 6, INTU, KIAA1284, PDZD6, PDZK6, INTU_HUMAN.
Background: Plays a key role in ciliogenesis and embryonic development. Regulator of cilia formation by controlling the organization of the apical actin cytoskeleton and the positioning of the basal bodies at the apical cell surface, which in turn is essential for the normal orientation of elongating ciliary microtubules. Plays a key role in definition of cell polarity via its role in ciliogenesis but not via conversion extension. Has an indirect effect on hedgehog signaling (By similarity). Proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (PubMed:27158779).
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ID gène
- 27152
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UniProt
- Q9ULD6
Antigène
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