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SLK anticorps (pTyr530)

SLK Reactivité: Souris, Rat ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN2179275
  • Antigène Voir toutes SLK Anticorps
    SLK (STE20-Like Kinase (SLK))
    Épitope
    • 15
    • 15
    • 14
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    pTyr530
    Reactivité
    • 45
    • 35
    • 19
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Souris, Rat
    Hôte
    • 58
    • 1
    Lapin
    Clonalité
    • 58
    • 1
    Polyclonal
    Conjugué
    • 16
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    Cet anticorp SLK est non-conjugé
    Application
    • 42
    • 38
    • 38
    • 14
    • 10
    • 8
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Souris, Rat
    Homologie
    Human,Dog,Cow,Pig,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic phosphopeptide derived from human FYN around the phosphorylation site of Tyr530
    Isotype
    IgG
    Top Product
    Discover our top product SLK Anticorps primaire
  • Indications d'application
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    SLK (STE20-Like Kinase (SLK))
    Autre désignation
    SLK (SLK Produits)
    Synonymes
    anticorps BcDNA:LD05623, anticorps CG40293, anticorps Dmel\\CG40293, anticorps LD05623, anticorps LOSK, anticorps STK2, anticorps bA16H23.1, anticorps se20-9, anticorps 9A2, anticorps AV021402, anticorps AW411554, anticorps Etk4, anticorps SMAK, anticorps Stk2, anticorps mKIAA0204, anticorps mSLK, anticorps STE20 like kinase, anticorps Ste20-like kinase, anticorps STE20-like kinase, anticorps SLK, anticorps Stlk, anticorps Slk
    Sujet

    Synonyms: Fyn phospho Y530, p-Fyn phospho Y530, C syn protooncogene, FYN oncogene related to SRC FGR YES_ MGC45350_ OKT3 induced calcium influx regulator_ P59 FYN, Protein tyrosine kinase fyn, Proto oncogene tyrosine protein kinase fyn, Protooncogene Syn, SLK, Src like kinase, Src yes related novel gene, Src/yes related novel gene, SYN, FYN, Tyrosine kinase p59fyn T, Tyrosine kinase p59fynT.

    Background: Fyn is a membrane-associated, non-receptor protein tyrosine kinase approximately 59 kDa, which belongs to the Src family of cytoplasmic tyrosine kinases. Fyn is very strongly similar to mouse Fyn, v-yes and c-src. Fyn is expressed predominately in tissues of neuronal and hematopoietic origin. Neuronal Fyn and hematopoietic Fyn differ at the junction of the SH2 and kinase domains due to tissue specific alternative splicing. Fyn has been shown to be involved in B cell and T cell activation as well as keratinocyte differentiation. In T cells, Fyn associates with the T-cell antigen receptor and Thy1. The unique N terminal domain of Fyn interacts with the CD3 and eta chains of the TcR. Fyn can bind to other proteins (p82 and p116) through its SH2 and SH3 domains, which may act as substrates or regulators of Fyn activity. Fyn is highly expressed in brain suggesting that it may have a role in the sensory nervous network and in myelination at early stages of CNS formation.

    ID gène
    2534
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