Superoxide dismutase copper chaperone anticorps (AA 201-274)

N° du produit ABIN2179351

Détail du produit anti-Superoxide dismutase copper chaperone anticorps

Antigène: Superoxide dismutase copper chaperone (CCS) (Copper Chaperone For Superoxide Dismutase (CCS))

Épitope: AA 201-274

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Superoxide dismutase copper chaperone est non-conjugé

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Homologie: Human,Mouse,Rat,Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human SOD4

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur Superoxide dismutase copper chaperone

Antigène: Superoxide dismutase copper chaperone (CCS) (Copper Chaperone For Superoxide Dismutase (CCS))

Autre désignation: SOD4/CCS (CCS Produits)

Synonymes: anticorps ccs, anticorps MGC82563, anticorps CCS, anticorps DDBDRAFT_0189222, anticorps DDBDRAFT_0238038, anticorps DDB_0189222, anticorps DDB_0238038, anticorps ATCCS, anticorps COPPER/ZINC SUPEROXIDE DISMUTASE COPPER CHAPERONE, anticorps F5O11.26, anticorps F5O11_26, anticorps copper chaperone for SOD1, anticorps Ccsd, anticorps copper chaperone for superoxide dismutase L homeolog, anticorps copper chaperone for superoxide dismutase, anticorps copper chaperone for SOD1, anticorps ccs.L, anticorps ccs, anticorps CCS, anticorps LOC552629, anticorps Ccs

Sujet:

Synonyms: CCS, CCS_HUMAN, Copper chaperone for superoxide dismutase, MGC138260, SOD 4, SOD4, Superoxide dismutase copper chaperone.

Background: Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn-SOD/SOD-1), mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, Zn-SOD (EC-SOD/SOD-3). SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit. The manganese containing 80 kDa tetrameric enzyme SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain. SOD3 is a heparin-binding multimer of disulfide-linked dimers, primarily expressed in human lungs, vessel walls and airways. SOD4 is a copper chaperone for superoxide dismutase (CCS), which specifically delivers Cu to copper/zinc superoxide dismutase. CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor.

ID gène: 9973

Pathways: Transition Metal Ion Homeostasis