Surface Layer Protein (AA 301-400) anticorps (Cy5)

N° du produit ABIN2179507

Cet anticorps Lapin Polyclonal détecte spécifiquement dans IF (cc) et IF (p). Il présente une réactivité envers Bactéries, Lactobacillus acidophilus, Lactobacillus amylovorus, Lactobacillus crispatus, Lactobacillus gallinarum et Lactobacillus helveticus.

Aperçu rapide pour Surface Layer Protein (AA 301-400) anticorps (Cy5) (ABIN2179507)

Antigène: Surface Layer Protein

Reactivité: Bactéries, Lactobacillus acidophilus, Lactobacillus amylovorus, Lactobacillus crispatus, Lactobacillus gallinarum, Lactobacillus helveticus

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cy5

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit

Épitope: AA 301-400

Réactivité croisée: Bactéries

Réactivité croisée (Details): L.acidophilus, L.crispatus, L.helveticus, L.amylovorus, L.gallinarum

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from L, acidophilus S-layer protein

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Surface Layer Protein

Sujet:

Synonyms: S-layer, Surface layer, surface layer protein, Slp, SLAP_LACAC, S-layer protein, slpA, sl pH , Lactobacillus surface layer protein,

Background: One of the most fascinating cell envelope structures in prokaryotic organisms is two-dimensional arrays of protein or glycoprotein subunits, termed S-layers (Surface Layers). They are composed of numerous identical subunits forming a symmetric, porous, lattice-like layer that completely covers the cell surface. The subunits are held together and attached to cell wall carbohydrates by non-covalent interactions, and they spontaneously reassemble in vitro by an entropy-driven process. In lactobacilli, S-layer proteins have been detected on many but not all species. Lactobacillus S-layer proteins differ from those of other bacteria in their smaller size and high predicted pI. The positive charge in Lactobacillus S-layer proteins is concentrated in the more conserved cell wall binding domain, which can be either N- or C-terminal depending on the species. The more variable domain is responsible for the self-assembly of the monomers to a periodic structure. The biological functions of Lactobacillus S-layer proteins are poorly understood, but in some species S-layer proteins mediate bacterial adherence to host cells or extracellular matrix proteins or have protective or enzymatic functions. Lactobacillus S-layer proteins show potential for use as antigen carriers in live oral vaccine design because of their adhesive and immunomodulatory properties and the general non-pathogenicity of the species.

ID gène: 3252774

UniProt: P35829