TSPAN12 anticorps (PE)

N° du produit ABIN2179842

Cet anticorps anti-TSPAN12 est un anticorps Lapin Polyclonal détectant TSPAN12 dans FACS. Adapté pour Humain, Rat et Souris.

Aperçu rapide pour TSPAN12 anticorps (PE) (ABIN2179842)

Antigène: TSPAN12 (Tetraspanin 12 (TSPAN12))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSPAN12 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-TSPAN12 anticorps (PE)

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TSPAN12

Isotype: IgG

Information d'application

Indications d'application: FCM: (1:20-100)
Optimal working dilution should be determined by the investigator.

Commentaires:

Exitation/Emission: 480,565nm/578nm

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 100 μg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at 4 °C for 12 months.

Détails sur TSPAN12

Antigène: TSPAN12 (Tetraspanin 12 (TSPAN12))

Autre désignation: Tspan12

Sujet: TSPAN12 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. It is a regulator of cell surface receptor signal transduction and plays a central role in retinal vascularization by regulating norrin (NDP) signal transduction. It acts in concert with norrin (NDP) to promote FZD4 multimerization and subsequent activation of FZD4, leading to promote accumulation of beta-catenin (CTNNB1) and stimulate LEF/TCF-mediated transcriptional programs. It also acts as a regulator of membrane proteinases such as ADAM10 and MMP14/MT1-MMP. It activates ADAM10-dependent cleavage activity of amyloid precursor protein (APP) and activates MMP14/MT1-MMP-dependent cleavage activity.
Synonyms: TSPAN 12, NET 2, NET2, Tetraspan NET 2, Tetraspanin 12, Tetraspanin12, TM4SF12, Transmembrane 4 superfamily member 12, TSN12_HUMAN.

ID gène: 23554