FERMT3 anticorps (AA 401-500) (Biotin)

N° du produit ABIN2179987

Cet anticorps Lapin Polyclonal détecte spécifiquement FERMT3 dans ELISA, IHC (p) et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour FERMT3 anticorps (AA 401-500) (Biotin) (ABIN2179987)

Antigène: FERMT3 (Fermitin Family Member 3 (FERMT3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FERMT3 est conjugé à/à la Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-FERMT3 anticorps (Biotin)

Épitope: AA 401-500

Homologie: Human,Mouse,Rat,Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human URP2

Isotype: IgG

Information d'application

Indications d'application: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur FERMT3

Antigène: FERMT3 (Fermitin Family Member 3 (FERMT3))

Autre désignation: URP2

Sujet:

Synonyms: Fermitin family homolog 3, Fermitin family member 3, FERMT3, Kind3, Kindlin 3, Kindlin-3, Kindlin3, MGC10966, MIG 2, MIG2 like protein, MIG2-like protein, MIG2B, Unc 112 related protein 2, Unc-112-related protein 2, UNC112C, URP2_HUMAN, URP2SF.

Background: Kindlin-3 is a 667 amino acid protein that localizes to both the cell membrane and the cytoplasm and contains one PH domain and one FERM domain. Expressed at high levels in lymph node tissue and at lower levels in spleen, thymus, stomach, placenta, lung, testis and small intestine, Kindlin-3 is thought to be involved in cell adhesion events and may play a role in apoptosis. Kindlin-3 is overexpressed in B-cell malignancies, suggesting that, via its ability to affect cell adhesion, Kindlin-3 may participate in tumor transformation and metastasis. Two isforms of Kindlin-3, designated short and long, exist due to alternative splicing events.