CD46 anticorps

N° du produit ABIN2191857

Détail du produit anti-CD46 anticorps

Antigène: CD46

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD46 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoassay (IA)

Réactivité croisée (Details): Cross reactivity: Rat CD46 : Yes

Stérilité: 0.2 μm filtered

Clone: MM10

Isotype: IgG2a

Information d'application

Indications d'application: For immune histology, flow cytometry and western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilution. The typical starting working dilution is 1:50. IA: Rat CD46 or mouse CD46 variant as coating on a micro titer plate Positive control

Restrictions: For Research Use only

Stockage

Buffer: PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.

Date de péremption: 12 months

Références pour anticorps anti-CD46 (ABIN2191857)

Frolikova, Otcenaskova, Valasková, Postlerova, Stopkova, Stopka, Komrskova: "The Role of Taste Receptor mTAS1R3 in Chemical Communication of Gametes." dans: International journal of molecular sciences, Vol. 21, Issue 7, (2020) (PubMed).

Détails sur CD46

Antigène: CD46

Autre désignation: Membrane Cofactor Protein (CD46 Produits)

Synonymes: anticorps AHUS2, anticorps MCP, anticorps MIC10, anticorps TLX, anticorps TRA2.10, anticorps Mcp, anticorps CD46, anticorps CD46 molecule, anticorps CD46 antigen, complement regulatory protein, anticorps CD46 molecule, complement regulatory protein, anticorps membrane cofactor protein-like, anticorps CD46, anticorps Cd46, anticorps LOC100341359, anticorps LOC103789310

Sujet: The monoclonal antibody MM10 recognizes membrane cofactor protein (MCP), also known as CD46. MCP is a type I membrane glycoprotein that consists of four isoforms i.e. two C-isoforms (51-58 kDa) and two BC isoforms (59-68 kDa) which arise by alternative splicing of a single CD46 gene. Membrane cofactor protein is expressed on every cell and tissue, with the exception of erythrocytes. Membrane cofactor protein serves to down-regulate the activation of complement on host tissue. MCP is a cofactor for factor 1-mediated cleavage of C3b and C4b and this way serves to protect the host cell against autologous attack. MCP is a receptor for several pathogens including measles virus, group A Streptococcus pyogenes and pathogenic Neisseria. Aliases MCP, CD46, Trophoblast leukocyte common antigen, TLX, measles virus receptor Immunogen Mouse CD46-human Fc fusion protein

Pathways: Regulation of Actin Filament Polymerization