Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

Caveolin-1 anticorps

CAV1 Reactivité: Rat WB Hôte: Souris Monoclonal 7C8 unconjugated
N° du produit ABIN2192105
  • Antigène Voir toutes Caveolin-1 (CAV1) Anticorps
    Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))
    Reactivité
    • 113
    • 67
    • 54
    • 15
    • 11
    • 9
    • 9
    • 9
    • 9
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Rat
    Hôte
    • 99
    • 16
    • 6
    • 2
    Souris
    Clonalité
    • 94
    • 29
    Monoclonal
    Conjugué
    • 87
    • 8
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Caveolin-1 est non-conjugé
    Application
    • 97
    • 38
    • 32
    • 29
    • 27
    • 17
    • 16
    • 16
    • 16
    • 11
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Stérilité
    0.2 μm filtered
    Clone
    7C8
    Top Product
    Discover our top product CAV1 Anticorps primaire
  • Indications d'application
    For Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. Positive Adipocytes (3T3-L1 adipocytes) control Negative Cytoplasmic extracts of adipocytes control
    Restrictions
    For Research Use only
  • Buffer
    PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for at least one year. The exact expiry date is indicated on the label.
  • Salani, Passalacqua, Maffioli, Briatore, Hamoudane, Contini, Cordera, Maggi: "IGF-IR internalizes with Caveolin-1 and PTRF/Cavin in HaCat cells." dans: PLoS ONE, Vol. 5, Issue 11, pp. e14157, (2010) (PubMed).

    Thoidis, Kotliar, Pilch: "Immunological analysis of GLUT4-enriched vesicles. Identification of novel proteins regulated by insulin and diabetes." dans: The Journal of biological chemistry, Vol. 268, Issue 16, pp. 11691-6, (1993) (PubMed).

  • Antigène
    Caveolin-1 (CAV1) (Caveolin 1, Caveolae Protein, 22kDa (CAV1))
    Autre désignation
    Caveolin-1 (CAV1 Produits)
    Synonymes
    anticorps fc07c04, anticorps wu:fc07c04, anticorps Cav-1, anticorps bscl3, anticorps cav1, anticorps cav1a, anticorps cgl3, anticorps vip21, anticorps cav1b, anticorps caveolin-1, anticorps cav, anticorps mstp085, anticorps Caveolin-1, anticorps CAV1, anticorps cav-1, anticorps Cav, anticorps caveolin 1, anticorps BSCL3, anticorps CGL3, anticorps MSTP085, anticorps PPH3, anticorps VIP21, anticorps caveolin 1, anticorps caveolin 1 L homeolog, anticorps caveolin 1 S homeolog, anticorps caveolin 1, caveolae protein, anticorps caveolin 1, caveolae protein, 22kDa, anticorps Caveolin, anticorps cav1, anticorps cav1.L, anticorps cav1.S, anticorps CAV1, anticorps Cav1, anticorps cav-1
    Sujet
    The monoclonal antibody 7C8 recognizes rat caveolin-1, a membrane protein of ~22 kDa. Caveolae are sphingomyelin/cholesterol-rich membrane domains first discovered as membrane invaginations on the surface of endothelial and epithelial cells. Caveolae are present in most cells, but are especially abundant in adipocytes. In addition to caveolins only two major protein components of caveolae were identified, namely the semicarbazide sensitive amine oxidase (SSAO) and the scavenger receptor CD36. Caveolin cycles between the plasma membrane and intracellular compartments via the endocytotic pathway. Caveolin is involved in the rapid intracellular transport of newly synthesized cholesterol from the ER directly to the caveolae. Caveolin plays an important role in multiple signaling pathways, molecular transport and cellular proliferation and differentiation. Caveolin binds to endothelial nitric oxide synthase leading to enzyme inhibition. Furthermore caveolin is a candidate tumor suppressor gene in many tumors. The specific functions of caveolin-1/caveolae are highly cell and context dependent. The monoclonal antibody 7C8 recognizes caveolin-1α as well as caveolin-1β, which are present in many tissues, like aorta, heart, muscle, lung, adipose white, brown and epidydimal fat. The monoclonal antibody 7C8 can be used to immuno-isolate caveolae. Immunogen GLUT4-containing vesicles immunoadsorbed from low density microsomes of rat adipocytes (Sprague Dawley) (Ref 4)
    Pathways
    Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Negative Regulation of Transporter Activity, VEGFR1 Specific Signals
Vous êtes ici:
Support technique