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Chips anticorps

Reactivité: Chemical WB, IHC (p), IHC (fro), Inhibition, IA, FACS Hôte: Souris Monoclonal JCC1 unconjugated
N° du produit ABIN2192149
  • Antigène
    Chips
    Reactivité
    Chemical
    Hôte
    • 2
    Souris
    Clonalité
    • 2
    Monoclonal
    Conjugué
    • 2
    Inconjugué
    Application
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Antibody (Inhibition), Immunoassay (IA), Flow Cytometry (FACS)
    Stérilité
    0.2 μm filtered
    Clone
    JCC1
  • Indications d'application
    For immunohistology, Western blot and flow cytometry dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10 for flow cytometry and 1:100 for Western blot and immunohistology. Before use in biological assays, the product must be filter sterilized and depending on the concentration to be used dialyzed against culture medium to remove the sodium azide added. Please inquire for availability of azide free solutions.
    Restrictions
    For Research Use only
  • Buffer
    PBS, containing 0.01 % sodium azide and 0.1 % BSA.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
    Date de péremption
    12 months
  • Antigène
    Chips
    Synonymes
    anticorps NI36_09680, anticorps chemotaxis inhibitory protein, anticorps NI36_RS09650
    Classe de substances
    Chemical
    Sujet
    The bacterial pathogen Staphylococcus aureus is insensitive to antimicrobial host defense peptides such as defensins, protegrins, platelet microbicidal proteins and bacteriocins. Staphylococci have developed various resistance mechanisms including those specific for bacteriocins and several host defense peptides. A protein belonging to the resistance mechanism of Staphylococcus aureus is known as CHIPS (Chemotaxis Inhibiting Protein of Staphylococcus aureus). CHIPS is a protein produced by Staphylococcus aureus that inhibits chemotaxis of neutrophils by blocking the Formyl Peptide Receptor (FPR) and C5a Receptor on neutrophils. CHIPS and antibodies against CHIPS can be useful for various experimental infection models of Staphylococcus aureus. Furthermore these reagents can be of help in studies on the role of FPR and C5a in inflammatory processes. Monoclonal antibody JCC1 reacts with the C-terminus of CHIPS.
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