CRISP3 anticorps

N° du produit ABIN2192192

L’anticorps Lapin Polyclonal anti-CRISP3 a été validé pour WB, IHC (p) et IA. Il convient pour détecter CRISP3 dans des échantillons de Humain. Il y a 3+ publications disponibles.

Aperçu rapide pour CRISP3 anticorps (ABIN2192192)

Antigène: CRISP3 (Cysteine-Rich Secretory Protein 3 (CRISP3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CRISP3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoassay (IA)

Détail du produit anti-CRISP3 anticorps

Stérilité: 0.2 μm filtered

Information d'application

Indications d'application: For Western blotting and immunohistology dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:10.

Restrictions: For Research Use only

Stockage

Buffer: PBS, containing 0.02 % sodium azide and 0.1 % bovine serum albumin.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.

Date de péremption: 12 months

Références pour anticorps anti-CRISP3 (ABIN2192192)

Udby, Cowland, Johnsen, Sørensen, Borregaard, Kjeldsen: "An ELISA for SGP28/CRISP-3, a cysteine-rich secretory protein in human neutrophils, plasma, and exocrine secretions." dans: Journal of immunological methods, Vol. 263, Issue 1-2, pp. 43-55, (2002) (PubMed).

Udby, Calafat, Sørensen, Borregaard, Kjeldsen: "Identification of human cysteine-rich secretory protein 3 (CRISP-3) as a matrix protein in a subset of peroxidase-negative granules of neutrophils and in the granules of eosinophils." dans: Journal of leukocyte biology, Vol. 72, Issue 3, pp. 462-9, (2002) (PubMed).

Kjeldsen, Cowland, Johnsen, Borregaard: "SGP28, a novel matrix glycoprotein in specific granules of human neutrophils with similarity to a human testis-specific gene product and a rodent sperm-coating glycoprotein." dans: FEBS letters, Vol. 380, Issue 3, pp. 246-50, (1996) (PubMed).

Détails sur CRISP3

Antigène: CRISP3 (Cysteine-Rich Secretory Protein 3 (CRISP3))

Autre désignation: Crisp-3

Sujet: Cysteine-rich secretory protein 3 (CRISP-3, also known as SGP28) is a glycoprotein that belongs to the family of cysteine-rich secretory proteins (CRISPs) which was originally discovered in human neutrophilic granulocytes. CRISP-3 is also widely distibuted in exocrine glands (salivary glands, pancreas and prostate), eosinophilic granulocytes and to a lower level in epididymis, ovary, thymus and colon. The presence of CRISP-3 in neutrophils, eosinophils and in exocrine secretions indicates a role in innate host defense. The antibody has been raised against recombinant C-terminally truncated form of CRISP-3 and recognizes both the N-glycosylated and non-glycosylated form of the mature protein.