Occludin anticorps

N° du produit ABIN2192203

Cet anticorps Cobaye Polyclonal détecte spécifiquement Occludin dans WB, IF et IHC (fro). Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour Occludin anticorps (ABIN2192203)

Antigène: Occludin (OCLN)

Reactivité: Humain

Hôte: Cobaye

Clonalité: Polyclonal

Conjugué: Cet anticorp Occludin est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Occludin anticorps

Stérilité: 0.2 μm filtered

Information d'application

Indications d'application: For immunohistology, immunfluorescence and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50..

Restrictions: For Research Use only

Stockage

Buffer: PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.

Date de péremption: 12 months

Références pour anticorps anti-Occludin (ABIN2192203)

Van Itallie, Anderson: "Occludin confers adhesiveness when expressed in fibroblasts." dans: Journal of cell science, Vol. 110 ( Pt 9), pp. 1113-21, (1997) (PubMed).

Détails sur Occludin

Antigène: Occludin (OCLN)

Autre désignation: Occludin

Sujet: The polyclonal antibody reacts with human occludin, an integral membrane protein specifically associated with tight junctions. These specialized regions of the plasma membrane prevent the diffusion of dissolved molecules between adjacent epithelial cells, seal off body cavities such as intestine or stomach lumen and prevent the diffusion of membrane proteins and glycolipids between the apical and basolateral regions of the plasma membrane. Occludin is localized at tight junctions of both epithelial and endothelial cells and is highly expressed in kidney and has not been detected in testis. On the cytoplasmic surface of occludin, a domain within the C-terminal 150 residues has been shown to bind directly to the well-characterized tight junction protein zona occludens 1 (ZO-1). The antibody is generated against recombinant human occludin (aa 358-504). The polyclonal anti- human occludin antibody cross reacts with rat, mouse and dog occludin.

Pathways: Cell-Cell Junction Organization, Hepatitis C