Occludin anticorps
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- Antigène Voir toutes Occludin (OCLN) Anticorps
- Occludin (OCLN)
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Reactivité
- Humain
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Hôte
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Cobaye
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Occludin est non-conjugé
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Stérilité
- 0.2 μm filtered
- Top Product
- Discover our top product OCLN Anticorps primaire
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- Indications d'application
- For immunohistology, immunfluorescence and Western blotting, dilutions to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50..
- Restrictions
- For Research Use only
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- Buffer
- PBS, containing 0.1 % bovine serum albumin and 0.02 % sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.
- Date de péremption
- 12 months
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Occludin confers adhesiveness when expressed in fibroblasts." dans: Journal of cell science, Vol. 110 ( Pt 9), pp. 1113-21, (1997) (PubMed).
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Occludin confers adhesiveness when expressed in fibroblasts." dans: Journal of cell science, Vol. 110 ( Pt 9), pp. 1113-21, (1997) (PubMed).
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- Antigène
- Occludin (OCLN)
- Autre désignation
- Occludin (OCLN Produits)
- Synonymes
- anticorps AI503564, anticorps Ocl, anticorps ocln, anticorps oclnb, anticorps tpmt, anticorps OCLN, anticorps wu:fd23h10, anticorps wu:fi13c01, anticorps zgc:113992, anticorps zgc:56359, anticorps BLCPMG, anticorps occludin, anticorps occludin S homeolog, anticorps occludin a, anticorps Ocln, anticorps OCLN, anticorps ocln.S, anticorps ocln, anticorps oclna
- Sujet
- The polyclonal antibody reacts with human occludin, an integral membrane protein specifically associated with tight junctions. These specialized regions of the plasma membrane prevent the diffusion of dissolved molecules between adjacent epithelial cells, seal off body cavities such as intestine or stomach lumen and prevent the diffusion of membrane proteins and glycolipids between the apical and basolateral regions of the plasma membrane. Occludin is localized at tight junctions of both epithelial and endothelial cells and is highly expressed in kidney and has not been detected in testis. On the cytoplasmic surface of occludin, a domain within the C-terminal 150 residues has been shown to bind directly to the well-characterized tight junction protein zona occludens 1 (ZO-1). The antibody is generated against recombinant human occludin (aa 358-504). The polyclonal anti- human occludin antibody cross reacts with rat, mouse and dog occludin.
- Pathways
- Cell-Cell Junction Organization, Hepatitis C
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