CMA1 anticorps

N° du produit ABIN228828

Cet anticorps anti-CMA1 est un anticorps Souris Monoclonal détectant CMA1 dans WB, IHC et IHC (p). Adapté pour Humain.

Aperçu rapide pour CMA1 anticorps (ABIN228828)

Antigène: CMA1 (Chymase 1, Mast Cell (CMA1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CMA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CMA1 anticorps

Specificité: May be used to detect mast cells in routinely fixed tissues and has been used to study the distribution of mast cells in skin, synovium, lung and heart. Binding of this antibody to chymase is not reduced in the presence of heparin, suggesting that the antibody does not bind to the heparin-binding domain of chymase. Species cross-reactivity: human.

Purification: Protein G purified

Immunogène: Purified human skin chymase.

Type of Immunogen: Purified protein

Isotype: IgG1

Information d'application

Indications d'application: Approved: IHC, IHC-P, WB

Usage: Western Blot1 (Ab 1-2 μg/mL for 2hrs at RT). Immunohistochemistry (Formalin/paraffin) (Use Ab at 0.06-0.12 μg/mL for 30 min at RT). Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min. Positive control: Tonsil. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM PBS,  pH 7.4.

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur CMA1

Antigène: CMA1 (Chymase 1, Mast Cell (CMA1))

Autre désignation: CMA1 / MCT1 / Chymase

Sujet: Name/Gene ID: CMA1
Subfamily: Serine S1
Family: Protease

Synonyms: CMA1, Chymase, Chymase, heart, Chymase, mast cell, CYH, Mast cell chymase, Mcpt5, MCT1, Mast cell protease 5, Mast cell protease I, Heart chymase, Alpha-chymase, Chymase 1, Chymase 1, mast cell, CYM

ID gène: 1215

UniProt: P23946

Pathways: ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis