Substance P anticorps (C-Term)

N° du produit ABIN230862

Cet anticorps anti-Substance P est un anticorps Rat Monoclonal détectant Substance P dans IHC, IHC (p), IHC (fro) et IF. Adapté pour Boeuf (Vache).

Aperçu rapide pour Substance P anticorps (C-Term) (ABIN230862)

Antigène: Substance P

Reactivité: Boeuf (Vache)

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Substance P est non-conjugé

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)

Clone: NC1-34

Détail du produit anti-Substance P anticorps

Épitope: C-Term

Specificité: Recognizes the COOH terminal end of substance P, a short polypeptide neurotransmitter that regulates the excitability of dorsal horn nociceptive neurons. It is known to have a role in several physiologic activities such as pain transmission, the vomiting reflex, salivary secretion and smooth muscle contraction. 5 % reactivity is observed with eledoisin. It does not react with Leu or Met-enkephalin, somatostatin or beta-endorphin.

Immunogène: Substance P conjugated to Bovine Serum Albumin.

Isotype: IgG2a

Information d'application

Indications d'application: Approved: IF, IHC, IHC-Fr (1:100 - 1:200), IHC-P (1:100 - 1:200)

Usage: Immunohistochemistry: This antibody has been used for the localization of substance P in tissue sections by immunofluorescence and PAP staining in nervous systems of experimental animals and man. Please refer to the Cuello references listed below. It has also been successfully applied in archive post-mortem tissues of the human brain, see Mai and Pioro references.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Tissue Culture Supernatant, 0.05 % Thimerosal.

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: 4°C or -20°C, Avoid freeze-thaw cycles.

Détails sur Substance P

Antigène: Substance P

Autre désignation: TAC1 / Substance P

Sujet: Name/Gene ID: TAC1
Family: Hormone

Synonyms: TAC1, Hs.2563, Neurokinin 1, Neurokinin 2, Neuromedin L, Neuropeptide K, NK2, NPK, Protachykinin beta, Protachykinin-1, Substance K, Substance P, Tachykinin, precursor 1, Neurokinin A, Neuropeptide gamma, PPT, Neurokinin alpha, NKA, NKNA, TAC2, Tachykinin 2

ID gène: 6863

UniProt: P20366