TMBIM1 anticorps (N-Term)

N° du produit ABIN233805

N° du produit (Fournisseur): 200-401-a57

Cet anticorps anti-TMBIM1 est un anticorps Lapin Polyclonal détectant TMBIM1 dans WB, ELISA et IHC. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour TMBIM1 anticorps (N-Term) (ABIN233805)

Antigène: TMBIM1 (Transmembrane BAX Inhibitor Motif Containing 1 (TMBIM1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TMBIM1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-TMBIM1 anticorps

Épitope: N-Term

N° du produit (Fournisseur): 200-401-a57

Fournisseur: Rockland

Fonction: TMBIM1 Antibody

Réactivité croisée (Details): This antibody is specific for human TMBIM1 protein.

Attributs du produit: Synonyms: rabbit anti-TMBIM1 Antibody, Putative uncharacterized protein TMBIM1, Protein lifeguard 3, Protein RECS1 homolog, Transmembrane BAX inhibitor motif-containing protein 1, LFG3, RECS1, PP1201, PSEC0158

Purification: This product was protein A purified from monospecific antiserum by immunoaffinity chromatography using protein A coupled to agarose beads.

Stérilité: Sterile filtered

Immunogène:

Immunogen: This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein corresponding to the amino terminus of human TMBIM1 protein.

Immunogen Type: Recombinant Protein

Isotype: IgG

Information d'application

Indications d'application:

Immunohistochemistry Dilution: 10 μg/mL

Application Note: This protein A purified antibody has been tested for use in ELISA, Immunohistochemistry, and western blotting.  Specific conditions for reactivity should be optimized by the end user.  Expect a band approximately 35 kDa in size corresponding to TMBIM-1 by western blotting in the appropriate cell lysate or extract.  To date this antibody has shown the ability to recognize over-expressed TMBIM1 but not endogenous protein.

Western Blot Dilution: 1:500 - 1:2,000

ELISA Dilution: 1:10,000

Other: User Optimized

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.2 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Références pour anticorps anti-TMBIM1 (ABIN233805)

Shukla, Fujita, Xiao, Liao, Garfield, Srinivasula: "A shear stress responsive gene product PP1201 protects against Fas-mediated apoptosis by reducing Fas expression on the cell surface." dans: Apoptosis : an international journal on programmed cell death, (2010) (PubMed).

Détails sur TMBIM1

Antigène: TMBIM1 (Transmembrane BAX Inhibitor Motif Containing 1 (TMBIM1))

Autre désignation: TMBIM1

Sujet: Background: This antibody is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI) and is suitable for Cancer, Immunology and Nuclear Signaling research. TMBIM1 (Transmembrane BAX inhibitor motif-containing protein 1) is a member of the 7 TMS (7 transmembrane domains) family of receptors known to mediate the activation of various transcription factors. TMBIM1 is identified as a novel modulator of NF-kB activation.  A drosophila homolog of this protein (dNMDA1 with 40 % homology to hTMBIM1) is reported to be unregulated during aging and oxidative stress.

ID gène: 64114, 50593008

UniProt: Q969X1