MYO1G anticorps (C-Term)

N° du produit ABIN233814

N° du produit (Fournisseur): 600-401-959

Cet anticorps anti-MYO1G est un anticorps Lapin Polyclonal détectant MYO1G dans WB, ELISA et IP. Adapté pour Humain. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour MYO1G anticorps (C-Term) (ABIN233814)

Antigène: MYO1G (Myosin IG (MYO1G))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MYO1G est non-conjugé

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Détail du produit anti-MYO1G anticorps

Épitope: C-Term

N° du produit (Fournisseur): 600-401-959

Fournisseur: Rockland

Fonction: Myosin 1G Antibody

Réactivité croisée (Details): This affinity-purified antibody is directed against human Myosin 1G protein.

Attributs du produit: Synonyms: rabbit anti-Myosin 1G antibody, Unconventional myosin-Ig, Minor histocompatibility antigen HA-2, mHag HA-2, MYO1G

Purification: The product was affinity purified from monospecific antiserum by immunoaffinity purification.

Stérilité: Sterile filtered

Immunogène:

Immunogen: This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a C-terminal region of human Myosin 1G protein.

Immunogen Type: Conjugated Peptide

Isotype: IgG

Information d'application

Indications d'application:

Application Note: This affinity-purified antibody has been tested for use in ELISA, western blotting and possibly in immunoprecipitation as well.  Specific conditions for reactivity should be optimized by the end user. By western blot a band approximately 100 kDa in size corresponding to Myosin 1G protein is expected in the appropriate cell lysate or extract.

Western Blot Dilution: 1:500 - 1:3,000

Immunoprecipitation Dilution: 1:100

ELISA Dilution: 1:10,000 - 1:40,000

Other: User Optimized

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.2 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Références pour anticorps anti-MYO1G (ABIN233814)

Olety, Wälte, Honnert, Schillers, Bähler: "Myosin 1G (Myo1G) is a haematopoietic specific myosin that localises to the plasma membrane and regulates cell elasticity." dans: FEBS letters, Vol. 584, Issue 3, pp. 493-9, (2010) (PubMed).

Détails sur MYO1G

Antigène: MYO1G (Myosin IG (MYO1G))

Autre désignation: MYO1G

Sujet: Background: This antibody is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI) and is suitable for Cancer, Immunology and Nuclear Signaling research. In general, myosins are protein complexes consisting of one or more myosin heavy chains, associated light chains and other proteins.  Myosins function as molecular motors and use the energy of ATP hydrolysis to move actin filaments or to move vesicles or other cargo on fixed actin filaments.  Myosins have magnesium-ATPase activity and bind actin. Myosins can be divided into classes that are distinguished based on sequence features of the motor, or head domain, but also have distinct tail regions that are believed to bind specific cargoes. Unconventional myosins exist.  Myosin 1G is an unconventional myosin that is restricted to hematopoietic cells. Unconventional myosins are also critical for motility in amoeba and a mammalian paralog (Myo1C) is critical as a glucose transporter that recycles glucose in response to insulin.

ID gène: 64005, 239582755

UniProt: B0I1T2