L’anticorps anti-Prekallikrein Monoclonal produit chez le Souris a été validé pour WB et ELISA. Il convient pour la détection de Prekallikrein dans des échantillons provenant de Humain.
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Recognizes two variants (88 kDa and 85 kDa) of prekallikrein and its activation products kallikrein (88 kDa and 85 kDa), the complexes formed by kallikrein with its endogenous inhibitors C1 inhibitor, alpha-2-macroglobulin and Antithrombin III, and 45 kDa prekallikrein/kallikrein fragment(s). Recognizes prekallikrein and its activation products in human, chimpanzee, rhesus, and baboon plasmas. The epitope for this antibody, located on the prekallikrein/kallikrein heavy chain, is involved in the interaction between prekallikrein and factor XIIa. This antibody inhibits prekallikrein activation in human and rhesus plasmas by approximately 60-80% and 55%, respectively. This antibody does not cross-react with tissue kallikrein.
Attributs du produit
MAb to Prekallikrein Heavy Chain, Monoclonal antibody to Prekallikrein Heavy Chain
PK
Reactivité: Humain
FACS
Hôte: Lapin
Polyclonal
PerCP
Indications d'application
Suitable for use in ELISA and Western blot. Note: Prekallikrein activation may occur with repeated freezing/thawing (3x or more) of plasma samples. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS, pH 7.4.
Agent conservateur
Without preservative
Conseil sur la manipulation
Avoid multiple freeze/thaw cycles. Centrifuge product if not completely clear after standing at room temperature. Prepare working dilution only prior to immediate use.