Prekallikrein anticorps (Heavy Chain)

N° du produit ABIN236108

Détail du produit anti-Prekallikrein anticorps

Antigène: Prekallikrein (PK)

Épitope: Heavy Chain

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Prekallikrein est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: Recognizes two variants (88 kDa and 85 kDa) of prekallikrein and its activation products kallikrein (88 kDa and 85 kDa), the complexes formed by kallikrein with its endogenous inhibitors C1 inhibitor, alpha-2-macroglobulin and Antithrombin III, and 45 kDa prekallikrein/kallikrein fragment(s). Recognizes prekallikrein and its activation products in human, chimpanzee, rhesus, and baboon plasmas. The epitope for this antibody, located on the prekallikrein/kallikrein heavy chain, is involved in the interaction between prekallikrein and factor XIIa. This antibody inhibits prekallikrein activation in human and rhesus plasmas by approximately 60-80% and 55%, respectively. This antibody does not cross-react with tissue kallikrein.

Attributs du produit: MAb to Prekallikrein Heavy Chain, Monoclonal antibody to Prekallikrein Heavy Chain

Purification: Protein G Chromatography. Ascites

Immunogène: Purified human plasma prekallikrein

Clone: 901

Isotype: IgG1

Information d'application

Indications d'application: Suitable for use in ELISA and Western blot. Note: Prekallikrein activation may occur with repeated freezing/thawing (3x or more) of plasma samples. Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid multiple freeze/thaw cycles.
Centrifuge product if not completely clear after standing at room temperature.
Prepare working dilution only prior to immediate use.

Stock: -20 °C

Stockage commentaire: Upon receipt, aliquot and store at -20 °C.

Détails sur Prekallikrein

Antigène: Prekallikrein (PK)

Autre désignation: Prekallikrein (PK Produits)