CEACAM20 anticorps
Aperçu rapide pour CEACAM20 anticorps (ABIN238330)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Purification
- Protein G
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Immunogène
- genetic immunisation with cDNA encoding human CEACAM20
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Isotype
- IgG1
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Indications d'application
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Flow cytometry: 1.2 µg/10^6 cells
Immunofluorescence: 1 µg/10^6 cells
CELISA: 1:200 - 1:400
For each application a titration should be performed to determine the optimal concentration. -
Restrictions
- For Research Use only
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Buffer
- PBS, pH 7.2
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C
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Stockage commentaire
- short term: 2 °C - 8 °C, long term: -20 °C
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- CEACAM20 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 20 (CEACAM20))
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Autre désignation
- CEACAM20
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Sujet
- CEA-related cell adhesion molecule 20 (CEACAM20) belongs to the carcinoembryonic antigen (CEA) gene family. It encodes a putative glycoprotein which is membrane-bound via a transmembrane domain. The CEACAM20 protein contains a single N domain followed by 4 immunoglobulin-like A (A1, A2) and B (B1, B2) domains. Expression of CEACAM20 can be found in tissues of prostate, testis, duodenum and small intestine with highest expression in prostate. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria. High expression of CEACAM20 in tissue of prostate carcinoma and in prostate carcinoma cell lines suggest that CEACAM20 can be used as a tumor marker.
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UniProt
- Q6UY09
Antigène
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