CTBP1 anticorps
Aperçu rapide pour CTBP1 anticorps (ABIN238338)
Antigène
Voir toutes CTBP1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- The polyclonal antibody reacts with CtBP1, a 49 kDa transcriptional corepressor, that plays a critical role in regulating gene expression.
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Purification
- Protein-A affinity chromatography.
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Immunogène
- Bacterially expressed recombinant human CtBP1.
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Indications d'application
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Immunoprecipitation. Western Blotting (Reducing conditions). Immunocytochemistry (1 μg/mL): acetone/methanol fixation.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, pH 7.4 with 15 mM sodium azide as preservative.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CTBP1 (C-terminal Binding Protein 1 (CTBP1))
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Autre désignation
- CTBP1
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Sujet
- C-terminal binding protein 1 / brefeldin A (BFA)-dependent ADP-ribosylation substrate (CtBP1/BARS) is a highly conserved transcriptional corepressor, that plays a critical role in regulating gene expression patterns throughout development and in oncogenesis. CtBP regulates target gene transcription, in part, via recruitment of histone deacetylases involved in gene silencing and may act to coordonate histone modifications that regulate gene expression.Synonyms: C-terminal-binding protein 1, CTBP
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ID gène
- 1487
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NCBI Accession
- NP_001319
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UniProt
- Q13363
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Pathways
- Retinoic Acid Receptor Signaling Pathway
Antigène
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