Clathrin Heavy Chain (CLTC) (Heavy Chain) anticorps

N° du produit ABIN238388

L’anticorps Souris Monoclonal anti- a été validé pour WB, IF, FACS, IP et EIA. Il convient pour détecter dans des échantillons de Humain, Souris, Rat, Boeuf (Vache) et Porc.

Aperçu rapide pour Clathrin Heavy Chain (CLTC) (Heavy Chain) anticorps (ABIN238388)

Antigène: Clathrin Heavy Chain (CLTC)

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Porc

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Clone: BF-06

Détail du produit

Épitope: Heavy Chain

Specificité: The antibody recognizes clathrin heavy chain, an ubiquitously expressed 180 kDa protein involved in receptor-mediated endocytosis.

Attributs du produit: Synonyms: CLTC, CLH17, CLTCL2, KIAA0034, Membrane Vesicle Marker, Clathrin heavy chain onchromosome 17

Purification: Ion exchange chromatography

Pureté: > 95 % (by SDS-PAGE)

Isotype: IgM

Information d'application

Indications d'application: Flow Cytometry: 2-5 μg/mL. Positive control: human blood leukocytes. Immunoprecipitation. Western Blotting. Immunocytochemistry. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Tris buffered saline (TBS) with 15 mM sodium azide, approx. pH 8.0

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody at 2 - 8 °C. Do not freeze.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détail du antigène

Antigène: Clathrin Heavy Chain (CLTC)

Autre désignation: Clathrin Heavy Chain

Sujet: Clathrin is a submembrane protein that polymerizes into coat-like lattices, which results in membrane invagination. The basic oligomers are composed of three clathrin heavy chain (180 kDa) and three light chain (30 kDa) subunits and the process of polymerization is dynamically regulated by the light chains. Interaction of clathrin with the plasma membrane is mediated by adaptor proteins (AP1-4) specific for different cellular compartments. Another proteins, such as endophilin, epsin and amphiphysin are involved in membrane invagination and clathrin rearrangements. Finally, dynamin functions at the fission stage of clathrin-mediated endocytosis.Synonyms: CLH17, CLTC, CLTCL2, Clathrin heavy chain on chromosome 17, KIAA0034, Membrane Vesicle Marker

ID gène: 1213

UniProt: Q00610