DAXX anticorps (His6)

N° du produit ABIN238399

Cet anticorps Souris Monoclonal détecte spécifiquement DAXX dans WB, IF et IP. Il présente une réactivité envers Humain.

Aperçu rapide pour DAXX anticorps (His6) (ABIN238399)

Antigène: DAXX (Death-Domain Associated Protein (DAXX))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DAXX est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Clone: DAXX-03

Détail du produit anti-DAXX anticorps

Épitope: AA 580-740, His6

Specificité: The antibody DAXX-03 reacts with C-terminal part of Daxx, a 110 kDa intracellular protein.

Attributs du produit: Synonyms: BING2, DAP6, EAP1, Death domain-associated protein 6, Fas death domain-associatedprotein, ETS1-associated protein 1

Purification: Protein A affinity chromatography.

Immunogène: His6-tagged protein corresponding to amino acids 580-740 of human Daxx.

Isotype: IgG1

Information d'application

Indications d'application: Immunoprecipitation. Western Blotting (2 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 with 15 mM sodium azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid freeze/thaw cycles.
Shelf life: One year from despatch.

Date de péremption: 12 months

Détails sur DAXX

Antigène: DAXX (Death-Domain Associated Protein (DAXX))

Autre désignation: DAXX

Sujet: Daxx is an apoptosis-modulating death-domain associated protein with functions in transcriptional regulation. Daxx functions bot in cytoplasm, where it interacts with Fas, and in nucleus (residing in PML oncogenic domains), where it is involved in SUMO-dependent regulation of transcription and subnuclear compartmentalization. Daxx senzitizes the cells to apoptosis, but on the other hand, this protein may also serve in preventing apoptosis in the early embryo. Even regarding the transcription, Daxx can serve both as a corepressor and a coactivator. During ischemic stress, Daxx translocates from the nucleus to the cytoplasm, where in regulates sodium hydrogen exchanger isoform 1 (NHE1).Synonyms: BING2, DAP6, Death domain-associated protein 6, EAP1, ETS1-associated protein 1, Fas death domain-associated protein

ID gène: 1616

UniProt: Q9UER7

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway