CD24 anticorps (PE)

N° du produit ABIN238503

Cet anticorps anti-CD24 est un anticorps Souris Monoclonal détectant CD24 dans FACS. Adapté pour Humain.

Aperçu rapide pour CD24 anticorps (PE) (ABIN238503)

Antigène: CD24 (CD24 Molecule (CD24))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD24 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: SN3

Détail du produit anti-CD24 anticorps (PE)

Attributs du produit: Synonyms: X62 heat stable antigen, HSA, Signal transducer CD24, Small cell lung carcinoma cluster 4antigen

Purification: Size-Exclusion Chromatography

Immunogène: Glycoproteins purified from human NALM-1 cell line.

Isotype: IgG1

Information d'application

Indications d'application: Suitable for Flow Cytometry analysis of human blood cells using 20 μL reagent / 100 μL ofwhole blood or 10^6 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS, 15 mM Sodium Azide, 0.2 % (w/v) high-grade BSA (protease free)

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody in the dark at 2-8 °C. Do Not Freeze! . Avoid prolonged exposure to light.
Shelf life: One year from despatch.

Date de péremption: 12 months

Détails sur CD24

Antigène: CD24 (CD24 Molecule (CD24))

Autre désignation: CD24

Sujet: CD24, also known as heat-stable antigen (HSA) or nectadorin, is a small mucin-like GPI-anchored extracellular membrane glycoprotein expressed on several cell types, including B cells. When B cells are activated and induced to further maturation, however, CD24 begins to disappear. CD24 seems to act as a gate-keeper for lipid rafts, thereby regulating the activity of integrins and other proteins such as the chemokine receptor CXCR4, it is also a ligand for P-selectin. CD24 triggering induces apoptosis of B cell precursors but not in mature resting B cells, where it instead inhibits their ability to proliferate in response to activation. CD24 expression is associated with invasiveness and poorer prognosis of carcinomas and is a marker of exosomes secreted into urine and amniotic fluid.Synonyms: HSA, Signal transducer CD24, Small cell lung carcinoma cluster 4 antigen, X62 heat stable antigen

UniProt: P25063

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation