IKbIP anticorps

N° du produit ABIN2423647

Cet anticorps Lapin Polyclonal détecte spécifiquement IKbIP dans IHC et ELISA. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour IKbIP anticorps (ABIN2423647)

Antigène: IKbIP (Inhibitor of KB Kinase beta Interacting Protein (IKbIP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IKbIP est non-conjugé

Application: Immunohistochemistry (IHC), ELISA

Détail du produit anti-IKbIP anticorps

Purification: Affinity purification

Immunogène: Recombinant protein of human IKBIP

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.4 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Conseil sur la manipulation: Avoid freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur IKbIP

Antigène: IKbIP (Inhibitor of KB Kinase beta Interacting Protein (IKbIP))

Autre désignation: IKBIP

Sujet: IKIP (Inhibitor of nuclear factor kappa-B kinase-interacting protein, IKK-interacting protein) is a single-pass membrane protein that shares a common promoter with APAF1. APAF1 and IKIP are both induced by X irradiation, however, the two gene products are transcribed in different directions. The IKIP gene is believed to be a target for p53 as expression of IKIP has been shown to promote apoptosis. IKIP has four known isoforms, three of which are found traversing the endoplasmic reticulum membrane. IKIP isoform 4 has a deletion of the transmembrane region which leads to a homogenous distribution of the protein within the cell. The IKIP gene products are expressed in vascular endothelial cells, while the isoform 4 has also been detected in lung, kidney, spleen, thymus and skeletal muscle.