SEPT4
Reactivité: Humain, Souris, Rat
ELISA, WB, IHC, ICC, IF
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
IHC 1:50-1:200
Restrictions
For Research Use only
Format
Liquid
Concentration
0.5 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Agent conservateur
Sodium azide
Conseil sur la manipulation
Avoid freeze / thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Antigène
Septin 4 (SEPT4)
Autre désignation
SEPT4
Sujet
This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct, it is localized to the mitochondria, and has a role in apoptosis and cancer.