ITGB7
Reactivité: Humain, Souris
FACS
Hôte: Rat
Monoclonal
FIB504
PE
Indications d'application
IHC 1:100-1:300
Restrictions
For Research Use only
Format
Liquid
Concentration
0.7 mg/mL
Buffer
PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4
Agent conservateur
Sodium azide
Conseil sur la manipulation
Avoid freeze / thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Antigène
Integrin beta 7 (ITGB7)
Autre désignation
ITGB7
Sujet
This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.