HIP1 anticorps (C-Term)

N° du produit ABIN2443742

L’anticorps anti-HIP1 Polyclonal Lapin est utilisé pour la détection de HIP1 dans des échantillons de Humain et Rat. Il a été validé pour WB et IF.

Aperçu rapide pour HIP1 anticorps (C-Term) (ABIN2443742)

Antigène: HIP1 (Huntingtin Interacting Protein 1 (HIP1))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HIP1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-HIP1 anticorps

Épitope: C-Term

Fonction: Huntingtin-Interacting Protein 1 (HIP1) Rabbit Polyclonal Antibody

Specificité: The antibody recognizes the C-terminal portion of HIP1

Purification: Purified

Immunogène: peptide in C term

Information d'application

Indications d'application: WB 1:500-1:2500,IF 1:10-1:100

Restrictions: For Research Use only

Stockage

Reconstitution: If diluted with deionized water in 100 μL: WB 1:500-1:2500, IF 1:10-1:100. Optimal dilution has to be determined by the user.

Buffer: Immunogen affinity purified in glycerol/PBS pH 7.4

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Antibodies diluted in glycerol can be kept at 4°C for up to 2 months and should be kept at -20°C for long-term storage (1 year). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. After the maximum long-term storage period (1 year -20°C or 2 months 4°C) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy.

Date de péremption: 12 months

Détails sur HIP1

Antigène: HIP1 (Huntingtin Interacting Protein 1 (HIP1))

Autre désignation: Huntingtin-Interacting Protein 1 (HIP1)

Sujet:

HIP1

Hungtinton's disease (HD) is an inherited neurodegenerative disorder characterized by the expression of an expanded polyglutamine tract in the protein huntingtin. HIP1 (huntingtin interacting protein 1) binds to normal huntingtin but this interaction is lost in HD. HIP1 also binds to components of clathrin-coated pits and vesicles and is a marker of clathrin-coated membranes. HIP1 expression levels are altered in several types of cancer.

UniProt: O00291

Pathways: Positive Regulation of Endopeptidase Activity