RhoGAP p190 (Catalytic Domain) anticorps

N° du produit ABIN2443768

Cet anticorps Lapin Polyclonal détecte spécifiquement RhoGAP p190 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour RhoGAP p190 (Catalytic Domain) anticorps (ABIN2443768)

Antigène: RhoGAP p190

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Application: Western Blotting (WB)

Détail du produit

Épitope: Catalytic Domain

Fonction: P190RhoGAP Rabbit Polyclonal Antibody

Specificité: The antibody recognizes the catalytic domain of the human P190RhoGAP protein (fragment of 82 kDa).

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: If reconstituted with deionized water in 50 μL: WB: 1:2000. Optimal dilution has to be determined by the user.

Buffer: Lyophilized serum

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.

Date de péremption: 24 months

Détail du antigène

Antigène: RhoGAP p190

Sujet:

GRLF1, Glucocorticoid Receptor DNA Binding Factor 1

P190RhoGAP, also known as GRLF1 (glucocorticoid receptor DNA binding factor 1) is a Rho family GTPase-activating protein that was identified as a protein that associates with p120RasGAP. P190RhoGAP is a multidomain protein that plays crucial role in regulating actin cytoskeletal rearrangements in axonal pathfinding and stability and in response to growth factor stimulation, integrin engagement, and v-Src transformation. Recently, it has been suggested that p190RhoGAP has also a role in regulating cell proliferation.

UniProt: Q9NRY4