Aconitase 1 anticorps (full length)

N° du produit ABIN2443828

Cet anticorps Lapin Polyclonal détecte spécifiquement Aconitase 1 dans WB. Il présente une réactivité avec des échantillons de Humain et Souris.Il a été cité dans 1 publication.

Aperçu rapide pour Aconitase 1 anticorps (full length) (ABIN2443828)

Antigène: Aconitase 1 (ACO1)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Aconitase 1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Aconitase 1 anticorps

Épitope: full length

Fonction: Iron Regulatory Protein 1 (IRP1) Rabbit Polyclonal Antibody

Specificité: The antibody recognizes the gull length IRP1 protein

Immunogène: Full length protein

Information d'application

Indications d'application: WB 1:2000

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: If reconstituted with deionized water in 50 μL: WB 1:2000. Optimal dilution has to be determined by the user.

Buffer: Lyophilized serum

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.

Date de péremption: 24 months

Références pour anticorps anti-Aconitase 1 (ABIN2443828)

Deng, Manz, Torti, Torti: "Iron-responsive element-binding protein 2 plays an essential role in regulating prostate cancer cell growth." dans: Oncotarget, Vol. 8, Issue 47, pp. 82231-82243, (2017) (PubMed).

Détails sur Aconitase 1

Antigène: Aconitase 1 (ACO1)

Autre désignation: Iron Regulatory Protein 1 (IRP1)

Sujet:

Iron-responsive element-binding proteins, IRE-BP, IRBP, IRP, IFR

The iron regulatory proteins IRP1 and IRP2 are involved in posttranscriptional regulation of cellular iron metabolism by binding to mRNA iron-responsive elements (IREs). IRPs respond to stress mediators, iron concentration and signaling factors, including nitrogen monoxide, cytokines and hydrogen peroxide. IRP-1 is a bifunctional soluble protein that functions as an IRE-binding protein or as the cytoplasmic isoform of aconitase.

UniProt: P21399

Pathways: Transition Metal Ion Homeostasis