CAN anticorps (small, Subunit B)

N° du produit ABIN2443839

Cet anticorps anti-CAN Monoclonal Souris (Clone VA1) (ABIN2443839) détecte spécifiquement CAN dans WB, IHC, IP, ELISA et ICC. L’anticorps est réactif avec des échantillons de Rat, Boeuf (Vache) et Lapin.

Aperçu rapide pour CAN anticorps (small, Subunit B) (ABIN2443839)

Antigène: CAN (Calcineurin (CAN))

Reactivité: Rat, Boeuf (Vache), Lapin

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CAN est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), ELISA, Immunocytochemistry (ICC)

Clone: VA1

Détail du produit anti-CAN anticorps

Épitope: small, Subunit B

Fonction: Calcineurin Mouse Monoclonal Antibody (VA1)

Specificité: The antibody recognizes the regulatory β-subunit of calcineurin

Purification: Protein G purified

Immunogène: Full lenght bovine protein

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: If reconstituted with deionized water in 100 μL: WB: 1:2000, ICC: 1:200. Optimal dilution has to be determined by the user.

Buffer: Lyophilized protein G purified in PBS pH 7.4

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.

Date de péremption: 24 months

Détails sur CAN

Antigène: CAN (Calcineurin (CAN))

Autre désignation: Calcineurin

Sujet:

Calcineurin beta-subunit

Within the last 30 years of research the biological roles of calcineurin have progressed from a putative inhibitor of the calmodulin dependent phosphodiesterase to the ground-breaking discovery that it is the target of immunosuppressant drugs such as cyclosporin A. As a serine/threonine protein phosphatase, calcineurin participates in a number of cellular processes and Ca2+ dependent signal transduction pathways. Calcineurin plays a key role in regulating the transcription factor NF-AT during T-cell activation, and in mediating responses of microorganisms to cation stress. Recently, this protein was studied extensively in relation to diseases such as schizophrenia and diabetes.

UniProt: P63099