tau anticorps (pSer208, pSer210)

N° du produit ABIN2443972

Cet anticorps Lapin Polyclonal détecte spécifiquement tau dans WB, ELISA et IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour tau anticorps (pSer208, pSer210) (ABIN2443972)

Antigène: tau (tau Protein)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp tau est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-tau anticorps

Épitope: pSer208, pSer210

Fonction: Phospho-Tau (ser 208/210) Rabbit Polyclonal Antibody

Specificité: The antibody recognizes the human Phospho-Tau protein peptide at the Serines 208 and 210 (Ser 208/210) phosphorylation site. (MW 48-67 kDa)

Purification: Immunogen affinity purified

Immunogène: Peptide phosphorylated at Ser 208 and Ser 210

Information d'application

Indications d'application: IHC 1:1000

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: If reconstituted with deionized water in 50 μL: WB: 1:10000, IHC 1:1000. Optimal dilution has to be determined by the user.

Buffer: Lyophilized immunogen affinity purified in PBS pH 7.4

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Lyophilized antibodies can be kept at 4°C for up to 3 months and should be kept at -20°C for long-term storage (2 years). To avoid freeze-thaw cycles, reconstituted antibodies should be aliquoted before freezing for long-term (1 year) storage (-80°C) or kept at 4°C for short-term usage (2 months). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made with the assay buffer. After the maximum long-term storage period (2 years lyophilized or 1 year reconstituted) antibodies should be tested in your assay with a standard sample to verify if you have noticed any decrease in their efficacy. To limit antibody loss or degradation, BSA (final concentration 1%) and sodium azide (final concentration 0.02%) can be added to the suggested first dilution. It is important to first verify if those preservatives are compatible with your assay.

Date de péremption: 24 months

Détails sur tau

Antigène: tau (tau Protein)

Autre désignation: tau

Sujet: Tauopathies are a group of diverse dementias and movement disorders which have a common pathological feature in that they all display the presence of intracellular accumulation of abnormal filaments of tau protein. Furthermore, these accumulated tau proteins all display an abnormal phosphorylation pattern that may be disease specific. As an example, Amyotrophic lateral sclerosis (ALS, also referred to as Charcot's disease or Lou Gehrig's disease) is the most common form of progressive motor neuron disease in North America. ALS gradually disables the patient's voluntary motor muscle control until it becomes fatal.

UniProt: P10636