FFAR1 anticorps (AA 210-222)

N° du produit ABIN2450556

Cet anticorps anti-FFAR1 est un anticorps Lapin Polyclonal détectant FFAR1 dans IHC. Adapté pour Humain.

Aperçu rapide pour FFAR1 anticorps (AA 210-222) (ABIN2450556)

Antigène: FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FFAR1 est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-FFAR1 anticorps

Épitope: AA 210-222

Specificité: GPR40 is a seven transmembrane G Protein-coupled receptor with signalling mediated by medium- and long-chain fatty acids. Found predominantly in the beta-cells of pancreatic islets, it has been implicated in the regulation of insulin secretion. Overexpression of GPR40 in mouse beta cells leads to glucose intolerance suggesting a link between GPR40 expression and diabetes. The receptor has also been identified as a possible mediator of oleate- and linoleate- stimulated proliferation of the human breast cancer cell line, MCF-7. GPR40 has a calculated mass of 31.4 kDa bases on its amino acid sequence.

Purification: Affinity purified

Immunogène: human GPR40 amino acids 210-222

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: TBS,  pH 7.4, containing 50 % glycerol, 0.5 mg/mL BSA, and 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C, stable for 1 year. Avoid freeze-thaw cycles.

Détails sur FFAR1

Antigène: FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))

Autre désignation: FFAR1 / GPR40

Sujet: Name/Gene ID: FFAR1
Subfamily: Carboxylic Acid
Family: GPCR

Synonyms: FFAR1, FFAR, FFA1R, G protein-coupled receptor 40, GPCR40, GPR40, Free fatty acid receptor, Free fatty acid receptor 1, G-protein coupled receptor 40

ID gène: 2864

Pathways: Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Carbohydrate Homeostasis