CBX5 anticorps (AA 179-191)

N° du produit ABIN2452033

Cet anticorps Lapin Polyclonal détecte spécifiquement CBX5 dans WB et IF. Il présente une réactivité avec des échantillons de Humain. Il a été cité dans 3+ publications.

Aperçu rapide pour CBX5 anticorps (AA 179-191) (ABIN2452033)

Antigène: CBX5 (Chromobox Homolog 5 (CBX5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CBX5 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Détail du produit anti-CBX5 anticorps

Épitope: AA 179-191

Réactivité croisée (Details): Not tested in other species.

Attributs du produit: The product is prepared by immunizing rabbit with the synthetic peptide CEDAENKEKETAKS corresponding to the amino acid sequence 179-191 of human HP1alpha and purified by affinity purification with the peptide. The antiserum was prepared by the direction of Prof. T. Haraguchi.

Purification: Affinity purified

Stérilité: Sterile filtered

Isotype: IgG

Information d'application

Indications d'application: 1) Western blotting: 1/1,000~1/3,000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.37 mg/mL

Buffer: 0.12 M sodium phosphate buffer ( pH 7.4), 50 % glycerol

Agent conservateur: Azide free

Stock: -20 °C/-80 °C

Stockage commentaire: -20 C (For long term storage: -70 C)

Références pour anticorps anti-CBX5 (ABIN2452033)

Lomberk, Wallrath, Urrutia: "The Heterochromatin Protein 1 family." dans: Genome biology, Vol. 7, Issue 7, pp. 228, (2007) (PubMed).

Wang, Koyama, Nishida, Haraguchi, Reith, Tsukamoto: "The assembly and maintenance of heterochromatin initiated by transgene repeats are independent of the RNA interference pathway in mammalian cells." dans: Molecular and cellular biology, Vol. 26, Issue 11, pp. 4028-40, (2006) (PubMed).

Kametaka, Takagi, Hayakawa, Haraguchi, Hiraoka, Yoneda: "Interaction of the chromatin compaction-inducing domain (LR domain) of Ki-67 antigen with HP1 proteins." dans: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 7, Issue 12, pp. 1231-42, (2002) (PubMed).

Détails sur CBX5

Antigène: CBX5 (Chromobox Homolog 5 (CBX5))

Autre désignation: HP1 alpha/cbx5

Sujet: Heterochromatin protein 1 (HP1) is a major component of heterochromatin and plays a role in assembly of various proteins on chromatin and gene silencing. The HP1 family is evolutionally conserved, with members in fungi, plants and animals but not prokaryotes, and there are multiple members within the same species. The HP1 family proteins are encoded by a class of genes known as the chromobox (CBX) genes. In humans, HP1alpha is encoded by the Chromobox homolog 5 (CBX5) gene located on chromosome 12q13.13. HP1alpha has been observed to interact directly or indirectly with several non-histone proteins with a wide variety of functions.

UniProt: P45973