Nas6/p28 anticorps

N° du produit ABIN2452055

Il existe 3+ publications pour ce produit. L’anticorps anti-Nas6/p28 Polyclonal Lapin est utilisé pour la détection de Nas6/p28 dans des échantillons de Saccharomyces cerevisiae. Il a été validé pour IP et WB.

Aperçu rapide pour Nas6/p28 anticorps (ABIN2452055)

Antigène: Nas6/p28

Reactivité: Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Application: Immunoprecipitation (IP), Western Blotting (WB)

Détail du produit

Réactivité croisée (Details): Not tested in other species.

Purification: Affinity purified

Immunogène: Recombinant yeast Nas6 expressed in E. coli

Isotype: IgG

Information d'application

Indications d'application: 1) Western blotting: 5000 fold dilution

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, 1 mg/mL BSA, 0.09 % sodium azide, 50 % glycerol

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Référence

Saeki, Toh-E, Kudo, Kawamura, Tanaka: "Multiple proteasome-interacting proteins assist the assembly of the yeast 19S regulatory particle." dans: Cell, Vol. 137, Issue 5, pp. 900-13, (2009) (PubMed).

Hori, Kato, Saeki, DeMartino, Slaughter, Takeuchi, Toh-e, Tanaka: "cDNA cloning and functional analysis of p28 (Nas6p) and p40.5 (Nas7p), two novel regulatory subunits of the 26S proteasome." dans: Gene, Vol. 216, Issue 1, pp. 113-22, (1998) (PubMed).

Hershko, Ciechanover: "The ubiquitin system." dans: Annual review of biochemistry, Vol. 67, pp. 425-79, (1998) (PubMed).

Détail du antigène

Antigène: Nas6/p28

Sujet: Background: The 26 S proteasome is a protein complex with a molecular mass of 2,000 kDa. It is essential not only for eliminating damaged or misfolded proteins but also for degrading short lived regulatory proteins involved in cell cycle regulation, DNA repair, signal transduction, apoptosis, and metabolic regulation. The 26S proteasome is composed of the 20S core particle (CP) and the 19S regulatory particle (RP). The RP is further subdivided into lid and base sub-complexes. NAS6 (p28) is a proteasome-interacting protein which acts as a chaperon to assemble the base sub-complex of the 19S RP. NAS6 is composed of 226 amino acid residues with calculated molecular masses of 24.4kD.