SNRPC anticorps (full length)

N° du produit ABIN2452159

Cet anticorps Rat Monoclonal détecte spécifiquement SNRPC dans WB, IP, IHC (p), ELISA et IF. Il présente une réactivité envers Souris et a été mentionné dans 2+ publications.

Aperçu rapide pour SNRPC anticorps (full length) (ABIN2452159)

Antigène: SNRPC (Small Nuclear Ribonucleoprotein Polypeptide C (SNRPC))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp SNRPC est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunofluorescence (IF)

Clone: 4H12

Détail du produit anti-SNRPC anticorps

Épitope: full length

Specificité: Specific to human, simian, and mouse U1C.

Réactivité croisée (Details): Not tested for other species

Purification: Purified

Stérilité: Sterile filtered

Immunogène: Recombinant GST-fused mouse U1C (full length)

Isotype: IgG2a kappa

Information d'application

Indications d'application: 1. Western blotting
2. Immunocytochemistry
3. Immunohistochemistry (frozen section)
4. ELISA
Other applications have not been tested.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol

Agent conservateur: Azide free

Stock: -20 °C/-80 °C

Stockage commentaire: -20 C (For long term storage: -70 C)

Références pour anticorps anti-SNRPC (ABIN2452159)

Pomeranz Krummel, Oubridge, Leung, Li, Nagai: "Crystal structure of human spliceosomal U1 snRNP at 5.5 A resolution." dans: Nature, Vol. 458, Issue 7237, pp. 475-80, (2009) (PubMed).

Muto, Pomeranz Krummel, Oubridge, Hernandez, Robinson, Neuhaus, Nagai: "The structure and biochemical properties of the human spliceosomal protein U1C." dans: Journal of molecular biology, Vol. 341, Issue 1, pp. 185-98, (2004) (PubMed).

Détails sur SNRPC

Antigène: SNRPC (Small Nuclear Ribonucleoprotein Polypeptide C (SNRPC))

Autre désignation: U1 SnRNP C (U1C)

Sujet: The spliceosomal U1C protein is critical to the initiation and regulation of precursor messenger RNA (pre-mRNA) splicing, as part of the U1 small nuclear ribonucleoprotein particle (snRNP). U1C is needed for efficient complex formation of U1 snRNP with a 5' splice site. The antibody was produced from the hybridoma cultured in serum-free medium and purified under mild conditions by propriety chromatography processes.

UniProt: Q62241, P09234

Pathways: Ribonucleoprotein Complex Subunit Organization