DPF3 anticorps

N° du produit ABIN2458080

Détail du produit anti-DPF3 anticorps

Antigène: DPF3 (D4, Zinc and Double PHD Fingers, Family 3 (DPF3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DPF3 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DPF3.

Information d'application

Indications d'application: DPF3 antibody can be used for detection of DPF3 by ELISA at 1:12500. DPF3 antibody can be used for detection of DPF3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store DPF3 antibody at -20 °C.

Détails sur DPF3

Antigène: DPF3 (D4, Zinc and Double PHD Fingers, Family 3 (DPF3))

Autre désignation: DPF3 (DPF3 Produits)

Synonymes: anticorps BAF45C, anticorps CERD4, anticorps 2810403B03Rik, anticorps 6530402L11Rik, anticorps C78788, anticorps cer-d4, anticorps si:ch211-268e23.1, anticorps wu:fj43h12, anticorps double PHD fingers 3, anticorps D4, zinc and double PHD fingers, family 3, anticorps DPF3, anticorps Dpf3, anticorps dpf3

Sujet: DPF3 is a muscle-specific component of the BAF complex, a multiprotein complex involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). DPF3 specifically binds acetylated lysines on histone 3 and 4 (H3K14ac, H3K9ac, H4K5ac, H4K8ac, H4K12ac, H4K16ac). In the complex, it acts as a tissue-specific anchor between histone acetylations and methylations and chromatin remodeling. It thereby probably plays an essential role in heart and skeletal muscle development.

Poids moléculaire: 40 kDa

ID gène: 8110

NCBI Accession: NP_036206

UniProt: Q92784