SUPT16H anticorps

N° du produit ABIN2458347

Détail du produit anti-SUPT16H anticorps

Antigène: SUPT16H (FACT complex subunit SPT16 (SUPT16H))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SUPT16H est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SUPT16H.

Information d'application

Indications d'application: SUPT16H antibody can be used for detection of SUPT16H by ELISA at 1:1562500. SUPT16H antibody can be used for detection of SUPT16H by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SUPT16H antibody at -20 °C.

Détails sur SUPT16H

Antigène: SUPT16H (FACT complex subunit SPT16 (SUPT16H))

Autre désignation: SUPT16H (SUPT16H Produits)

Synonymes: anticorps CDC68, anticorps FACTP140, anticorps SPT16/CDC68, anticorps CG1828, anticorps DRE4/dSPT16, anticorps Dmel\\CG1828, anticorps SPT16, anticorps Spt16, anticorps dSPT16, anticorps dSpt16, anticorps dspt16, anticorps l(3)62Bg, anticorps l(3)dre4, anticorps spt16, anticorps Cdc68, anticorps Fact140, anticorps Supt16h, anticorps T12H20.3, anticorps T12H20_3, anticorps global transcription factor C, anticorps SSF1, anticorps DDBDRAFT_0204912, anticorps DDBDRAFT_0231753, anticorps DDB_0204912, anticorps DDB_0231753, anticorps DUF140, anticorps SPT16 homolog, facilitates chromatin remodeling subunit, anticorps FACT complex subunit spt16, anticorps FACT complex subunit SPT16, anticorps CG1828 gene product from transcript CG1828-RB, anticorps suppressor of Ty 16, anticorps global transcription factor C, anticorps chromatin-remodeling protein SPT16, anticorps FACT complex component Spt16, anticorps chromatin-remodeling protein, anticorps global regulator of transcription, anticorps FACT (FAcilitates Chromatin Transcription) complex subunit, putative, anticorps SPT16 homolog, facilitates chromatin remodeling subunit S homeolog, anticorps SUPT16H, anticorps AOR_1_1808194, anticorps CC1G_05155, anticorps dre4, anticorps Supt16, anticorps SPT16, anticorps spt16, anticorps CDC68, anticorps Supt16h, anticorps supt16h, anticorps supt16h.S

Sujet: Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit, the latter of which is SUPT16H. Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit, the latter of which is the protein encoded by this gene. Sequence Note: The sequence AF152961.1 is a chimeric mRNA clone. Only the SUPT16H region was propagated into this RefSeq record. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Poids moléculaire: 120 kDa

ID gène: 11198

NCBI Accession: NP_009123

UniProt: Q9Y5B9

Pathways: Chromatin Binding