PPP4R2 anticorps

N° du produit ABIN2458684

Détail du produit anti-PPP4R2 anticorps

Antigène: PPP4R2 (Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPP4R2 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PPP4R2.

Information d'application

Indications d'application: PPP4R2 antibody can be used for detection of PPP4R2 by ELISA at 1:62500. PPP4R2 antibody can be used for detection of PPP4R2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PPP4R2 antibody at -20 °C.

Détails sur PPP4R2

Antigène: PPP4R2 (Protein Phosphatase 4, Regulatory Subunit 2 (PPP4R2))

Autre désignation: PPP4R2 (PPP4R2 Produits)

Synonymes: anticorps PP4R2, anticorps BE691708, anticorps C230060M08Rik, anticorps ppp4r2, anticorps fe11b04, anticorps wu:fe11b04, anticorps ppp4r2-B, anticorps wu:fa17h08, anticorps wu:fc23g05, anticorps protein phosphatase 4 regulatory subunit 2, anticorps protein phosphatase 4, regulatory subunit 2, anticorps protein phosphatase 4, regulatory subunit 2a, anticorps protein phosphatase 4 regulatory subunit 2 S homeolog, anticorps protein phosphatase 4 regulatory subunit 2 L homeolog, anticorps protein phosphatase 4, regulatory subunit 2b, anticorps PPP4R2, anticorps Ppp4r2, anticorps ppp4r2a, anticorps ppp4r2.S, anticorps ppp4r2, anticorps ppp4r2.L, anticorps ppp4r2b

Sujet: PPP4R2 is the regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). It may regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.

Poids moléculaire: 47 kDa

ID gène: 151987

NCBI Accession: NP_777567

UniProt: Q9NY27