SPTLC2 antibody can be used for detection of SPTLC2 by ELISA at 1:312500. SPTLC2 antibody can be used for detection of SPTLC2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.
Concentration
1 mg/mL
Buffer
Antibody is lyophilized in PBS buffer with 2 % sucrose.
Conseil sur la manipulation
As with any antibody avoid repeat freeze-thaw cycles.
Stock
4 °C/-20 °C
Stockage commentaire
For short periods of storage (days) store at 4 °C. For longer periods of storage, store SPTLC2 antibody at -20 °C.
Antigène
SPTLC2
(serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))
anticorps HSN1C, anticorps LCB2, anticorps LCB2A, anticorps NSAN1C, anticorps SPT2, anticorps hLCB2a, anticorps sptlc2, anticorps zgc:110661, anticorps AI173915, anticorps mKIAA0526, anticorps Pomt2, anticorps LCB2a, anticorps SPTLC2, anticorps serine palmitoyltransferase long chain base subunit 2, anticorps serine palmitoyltransferase 2, anticorps serine palmitoyltransferase, long chain base subunit 2 S homeolog, anticorps serine palmitoyltransferase, long chain base subunit 2a, anticorps serine palmitoyltransferase, long chain base subunit 2, anticorps SPTLC2, anticorps LOC100446763, anticorps sptlc2, anticorps sptlc2.S, anticorps sptlc2a, anticorps Sptlc2
Sujet
SPTLC2 is a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. Alternatively spliced variants encoding different isoforms have been identified.