XYLT2 anticorps

N° du produit ABIN2459323

Cet anticorps Lapin Polyclonal détecte spécifiquement XYLT2 dans WB et ELISA. Il présente une réactivité envers Souris, Humain, Chien et Rat.

Aperçu rapide pour XYLT2 anticorps (ABIN2459323)

Antigène: XYLT2 (Xylosyltransferase II (XYLT2))

Reactivité: Souris, Humain, Chien, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp XYLT2 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-XYLT2 anticorps

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human XYLT2.

Information d'application

Indications d'application: XYLT2 antibody can be used for detection of XYLT2 by ELISA at 1:312500. XYLT2 antibody can be used for detection of XYLT2 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store XYLT2 antibody at -20 °C.

Détails sur XYLT2

Antigène: XYLT2 (Xylosyltransferase II (XYLT2))

Autre désignation: XYLT2

Sujet: XYLT2 is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis.The protein encoded by this gene is an isoform of xylosyltransferase, which belongs to a family of glycosyltransferases. This enzyme transfers xylose from UDP-xylose to specific serine residues of the core protein and initiates the biosynthesis of glycosaminoglycan chains in proteoglycans including chondroitin sulfate, heparan sulfate, heparin and dermatan sulfate. The enzyme activity, which is increased in scleroderma patients, is a diagnostic marker for the determination of sclerotic activity in systemic sclerosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Poids moléculaire: 97 kDa

ID gène: 64132

NCBI Accession: NP_071450

UniProt: Q9H1B5

Pathways: Glycosaminoglycan Metabolic Process