ACTR1A anticorps

N° du produit ABIN2460043

Cet anticorps Lapin Polyclonal détecte spécifiquement ACTR1A dans WB et ELISA. Il présente une réactivité envers Humain, Souris, Rat et Chien.

Aperçu rapide pour ACTR1A anticorps (ABIN2460043)

Antigène: ACTR1A (Alpha Centractin (ACTR1A))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACTR1A est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ACTR1A anticorps

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ACTR1A.

Information d'application

Indications d'application: ACTR1A antibody can be used for detection of ACTR1A by ELISA at 1:62500. ACTR1A antibody can be used for detection of ACTR1A by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ACTR1A antibody at -20 °C.

Détails sur ACTR1A

Antigène: ACTR1A (Alpha Centractin (ACTR1A))

Autre désignation: ACTR1A

Sujet: ACTR1A is a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60 % identical at the amino acid level to conventional actin.This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60 % identical at the amino acid level to conventional actin. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Poids moléculaire: 41 kDa

ID gène: 10121

NCBI Accession: NP_005727

UniProt: P61163

Pathways: M Phase