NFYA anticorps

N° du produit ABIN2460199

Cet anticorps Lapin Polyclonal détecte spécifiquement NFYA dans WB, ELISA et IHC. Il présente une réactivité envers Humain, Souris, Rat et Chien.

Aperçu rapide pour NFYA anticorps (ABIN2460199)

Antigène: NFYA (Nuclear Transcription Factor Y, alpha (NFYA))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFYA est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-NFYA anticorps

Purification: Antibody is supplied as total IgG.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NFYA.

Information d'application

Indications d'application: NFYA antibody can be used for detection of NFYA by ELISA at 1:312500. NFYA antibody can be used for detection of NFYA by western blot at 5.0-8.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 200 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store NFYA antibody at -20 °C.

Détails sur NFYA

Antigène: NFYA (Nuclear Transcription Factor Y, alpha (NFYA))

Autre désignation: NFYA

Sujet: NFYA is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms.

Poids moléculaire: 37 kDa, 34 kDa

ID gène: 4800

NCBI Accession: NP_002496

UniProt: P23511

Pathways: Regulation of Lipid Metabolism by PPARalpha