MXI1 anticorps

N° du produit ABIN2460213

Détail du produit anti-MXI1 anticorps

Antigène: MXI1 (MAX Interactor 1 (MXI1))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MXI1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MXI1.

Information d'application

Indications d'application: MXI1 antibody can be used for detection of MXI1 by ELISA at 1:312500. MXI1 antibody can be used for detection of MXI1 by western blot at 1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MXI1 antibody at -20 °C.

Détails sur MXI1

Antigène: MXI1 (MAX Interactor 1 (MXI1))

Autre désignation: MXI1 (MXI1 Produits)

Synonymes: anticorps mxi, anticorps mad2, anticorps mxd2, anticorps xmxi1, anticorps MGC89544, anticorps MXI1, anticorps etID309773.22, anticorps fb16b12, anticorps fb55f03, anticorps wu:fb16b12, anticorps wu:fb55f03, anticorps wu:fd06a08, anticorps wu:fz74f10, anticorps ENSMUSG00000067085, anticorps Gm10197, anticorps Mad2, anticorps bHLHc11, anticorps MXI-WR, anticorps MAD2, anticorps MXD2, anticorps MXI, anticorps MAX interactor 1, dimerization protein, anticorps max interactor 1, dimerization protein, anticorps MAX interactor 1, dimerization protein L homeolog, anticorps mxi1, anticorps MXI1, anticorps Mxi1, anticorps mxi1.L

Sujet: Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The MXI1 gene encodes a transcriptional repressor protein thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in MXI1 are frequently found in patients with prostate tumors.Expression of the c-myc gene, which produces an oncogenic transcription factor, is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function, and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX, another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally.

Poids moléculaire: 26 kDa, 21 kDa, 33 kDa

ID gène: 4601

NCBI Accession: NP_005953

UniProt: P50539

Pathways: Maintenance of Protein Location