MTF1 anticorps

N° du produit ABIN2460357

Cet anticorps anti-MTF1 est un anticorps Lapin Polyclonal détectant MTF1 dans WB et ELISA. Adapté pour Humain, Souris, Rat et Chien.

Aperçu rapide pour MTF1 anticorps (ABIN2460357)

Antigène: MTF1 (Metal-Regulatory Transcription Factor 1 (MTF1))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MTF1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-MTF1 anticorps

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MTF1.

Information d'application

Indications d'application: MTF1 antibody can be used for detection of MTF1 by ELISA at 1:2500. MTF1 antibody can be used for detection of MTF1 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MTF1 antibody at -20 °C.

Détails sur MTF1

Antigène: MTF1 (Metal-Regulatory Transcription Factor 1 (MTF1))

Autre désignation: MTF1

Sujet: The zinc finger transcription factor MTF-1 (metal-responsive transcription factor-1) is conserved from insects to vertebrates. The major role of MTF-1 in both organisms is to control the transcription of genes involved in the homeostasis and detoxification of heavy metal ions such as Cu2+, Zn2+ and Cd2+. In mammals, MTF-1 serves at least two additional roles. First, targeted disruption of the MTF-1 gene results in death at embryonic day 14 due to liver degeneration, revealing a stage-specific developmental role. Second, under hypoxic-anoxic stress, MTF-1 helps to activate the transcription of the gene placental growth factor (PIGF), an angiogenic protein.

Poids moléculaire: 81 kDa

ID gène: 4520

NCBI Accession: NP_005946

UniProt: Q14872