MTF1 anticorps
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- Antigène Voir toutes MTF1 Anticorps
- MTF1 (Metal-Regulatory Transcription Factor 1 (MTF1))
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Reactivité
- Humain, Souris, Chien, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp MTF1 est non-conjugé
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Application
- Western Blotting (WB), ELISA
- Purification
- Antibody is purified by protein A chromatography method.
- Immunogène
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MTF1.
- Top Product
- Discover our top product MTF1 Anticorps primaire
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- Indications d'application
- MTF1 antibody can be used for detection of MTF1 by ELISA at 1:2500. MTF1 antibody can be used for detection of MTF1 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
- Concentration
- 1 mg/mL
- Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
- Conseil sur la manipulation
- As with any antibody avoid repeat freeze-thaw cycles.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store MTF1 antibody at -20 °C.
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- Antigène
- MTF1 (Metal-Regulatory Transcription Factor 1 (MTF1))
- Autre désignation
- MTF1 (MTF1 Produits)
- Synonymes
- anticorps MTF-1, anticorps MTF1, anticorps mtf1, anticorps MGC86485, anticorps Thyls, anticorps ZRF, anticorps metal regulatory transcription factor 1, anticorps metal-regulatory transcription factor 1, anticorps metal-regulatory transcription factor 1 L homeolog, anticorps metal response element binding transcription factor 1, anticorps MTF1, anticorps mtf1, anticorps mtf1.L, anticorps Mtf1
- Sujet
- The zinc finger transcription factor MTF-1 (metal-responsive transcription factor-1) is conserved from insects to vertebrates. The major role of MTF-1 in both organisms is to control the transcription of genes involved in the homeostasis and detoxification of heavy metal ions such as Cu2+, Zn2+ and Cd2+. In mammals, MTF-1 serves at least two additional roles. First, targeted disruption of the MTF-1 gene results in death at embryonic day 14 due to liver degeneration, revealing a stage-specific developmental role. Second, under hypoxic-anoxic stress, MTF-1 helps to activate the transcription of the gene placental growth factor (PIGF), an angiogenic protein.
- Poids moléculaire
- 81 kDa
- ID gène
- 4520
- NCBI Accession
- NP_005946
- UniProt
- Q14872
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