SNW1 anticorps

N° du produit ABIN2460414

Cet anticorps anti-SNW1 est un anticorps Lapin Polyclonal détectant SNW1 dans WB, IHC et ELISA. Adapté pour Humain, Chien et Rat.

Aperçu rapide pour SNW1 anticorps (ABIN2460414)

Antigène: SNW1 (SNW Domain Containing 1 (SNW1))

Reactivité: Humain, Chien, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNW1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-SNW1 anticorps

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SKIIP.

Information d'application

Indications d'application: SKIIP antibody can be used for detection of SKIIP by ELISA at 1:62500. SKIIP antibody can be used for detection of SKIIP by western blot at 1.0-5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SKIIP antibody at -20 °C.

Détails sur SNW1

Antigène: SNW1 (SNW Domain Containing 1 (SNW1))

Autre désignation: SKIIP

Sujet: SKIIP (Nuclear Protein SkiP, nuclear receptor coactivator NCoA-62, ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly (A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity.

Poids moléculaire: 61 kDa

ID gène: 22938

NCBI Accession: NP_036377

UniProt: Q13573

Pathways: Retinoic Acid Receptor Signaling Pathway