Paired Box 3 anticorps
Aperçu rapide pour Paired Box 3 anticorps (ABIN2460470)
Antigène
Voir toutes Paired Box 3 (PAX3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Purification
- Antibody is purified by protein A chromatography method.
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Immunogène
- Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PAX3.
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Indications d'application
- PAX3 antibody can be used for detection of PAX3 by ELISA at 1:312500. PAX3 antibody can be used for detection of PAX3 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.
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Concentration
- 1 mg/mL
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Buffer
- Antibody is lyophilized in PBS buffer with 2 % sucrose.
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Conseil sur la manipulation
- As with any antibody avoid repeat freeze-thaw cycles.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- For short periods of storage (days) store at 4 °C. For longer periods of storage, store PAX3 antibody at -20 °C.
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- Paired Box 3 (PAX3)
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Autre désignation
- PAX3
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Sujet
- PAX3 is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t (2,13) (q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma.
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Poids moléculaire
- 45 kDa
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ID gène
- 5077
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NCBI Accession
- NP_852126
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UniProt
- Q86UQ3
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Pathways
- Sensory Perception of Sound, Tube Formation
Antigène
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