MIER1 anticorps

N° du produit ABIN2460961

Cet anticorps Lapin Polyclonal détecte spécifiquement MIER1 dans WB et ELISA. Il présente une réactivité envers Humain, Souris, Rat, Chien et Poisson zèbre (Danio rerio).

Aperçu rapide pour MIER1 anticorps (ABIN2460961)

Antigène: MIER1 (Mesoderm Induction Early Response 1 (MIER1))

Reactivité: Humain, Souris, Rat, Chien, Poisson zèbre (Danio rerio)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MIER1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-MIER1 anticorps

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MIER1.

Information d'application

Indications d'application: MIER1 antibody can be used for detection of MIER1 by ELISA at 1:312500. MIER1 antibody can be used for detection of MIER1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MIER1 antibody at -20 °C.

Détails sur MIER1

Antigène: MIER1 (Mesoderm Induction Early Response 1 (MIER1))

Autre désignation: MIER1

Sujet: The association of hMI-ER1 with Sp1 represents a novel mechanism for the negative regulation of Sp1 target promoters. Results demonstrate that alternate use of a facultative intron regulates the subcellular localization of hMI-ER1 proteins and this may have important implications for hMI-ER1 function in the regulation of transcription. Repressor activity is due to interaction and recruitment of a trichostatin A-sensitive histone deacetylase 1 (HDAC1).

Poids moléculaire: 49 kDa

ID gène: 57708

NCBI Accession: NP_065999

UniProt: Q8NES5

Pathways: Chromatin Binding